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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

卓越雇主排名:68
6. Am I maintaining healthy relationships? Is there a relationship in your life that needs a little extra care and attention? Do you need to right a wrong with someone? Try to stay aware of how you’re treating the people in your life.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

“It’s na瘀攀 not to recognize we’re at a pretty serious moment,” said Anthony Crichton-Stuart, director of the London dealer Agnew’s. “There has been a massive taste shift. But when a good old master does come up at auction and it is priced correctly, you do get some excitement.”
补救办法:当我们在做出重大决定时,例如接受(或拒绝)工作邀请时,我们往往会受到信息性偏见的影响。如果我们认为自己做出了正确的选择,就首先会想到那些支持这种想法的信息。但如果我们担心自己犯了错误,我们的潜意识就会增强这种直觉。在做出工作的决定时,如果你习惯性地怀疑自己的能力,这个问题不在于你以前所做的职业选择是否正确,而在于你需要建立自信,相信自己有能力选择让自己满意的职业,并对结果有一定的把握。若要解决这个问题,需要回忆你在做出这个选择时所处的环境和当时你所优先考虑的因素,然后看看现在所处的环境和优先考虑的因素是否发生了变化。此外还要与职业顾问合作,理清工作决策,帮助你增强进入新领域的信心、承担风险和谈判的能力。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

节目28 歌曲《留声2012》①《滴答》(表演者:侃侃、李晨)②《我的歌声里》(表演者:曲婉婷、杜淳)

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

米特卜王子被捕不到一个月即获释,这显示出沙特想要迅速结束这场腐败调查,阿尔瓦利德·本·塔拉尔王子等多名王室成员和亿万富翁在调查中突然被捕。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

He said game and live-broadcast apps currently hosted by Tencent don't require real-name registration, but the company is considering establishing a platform for parents to monitor their children's behavior.
This is all bad news for investors, just as America's 30-year bond bull is ending.
奥巴马将迎来第二个任期,摆在他面前的任务依然很艰巨:如何处理1万亿美元的高额年度财政赤字,如何削减高达16万亿美元的国债,如何改革开支高昂的社会事业,如何应对党派斗争激烈陷入僵局的美国国会等等。
But a friend saw a TV report about it and contacted the sorting office. Mr Siddeeq, 74, says he is still eager to read it, despite now being divorced。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

n. 航行,航海,导航
Even if Gibson turns out to be a rental and leaves as a free agent this summer, the Thunder will likely feel good about these trade terms.
Payouts also varied substantially between industries and cities. The average bonus at financial institutions was over Rmb17,200, while those in the education sector got less than half of that on average at less than Rmb7,500.
2010年英文新年祝福邮件

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

在美国发起反倾销案件比在欧盟容易得多。在欧盟,企业必须先通过公众利益测试。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

对于购房者,也不都是坏消息:房价明年(2015年——译注)仍将上涨,但步伐可能会从飙涨趋于平缓。“房价不会一味地陡然上涨,”柯克兰集团(Corcoran)的首席执行官帕梅拉·利伯曼(Pamela Liebman)说,“买家都有点疲劳了。”

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

考虑到达拉斯多年来一直拒绝摆滥,当德克-诺维茨基的职业生涯进入倒计时阶段,他们并没有囤积足够多的潜力新秀,这时换来22岁的诺埃尔而且没有对常规轮换造成大的损伤是个相当高明的举动。
在接受《第一财经》采访时,中国建设银行(CCB)董事长提到,中国各银行面对的最大挑战在于不良贷款不断上升。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

国考报名将于本月24日截止,而考试将于11月27日在中国各大城市举行。
“The consumer will take a little more time to come back which is why we’re focusing on a game plan we know that works, focusing on affordability and premium [drinks] in metro areas,” he said, adding that he is confident that the company can continue to gain share in the country and is set up for when consumer spending picks up again.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Song “Fire In The Winter”(Kenji Wu and Dream Chorus)
作为回应,维尔德斯把吕特归为骗子,指责后者未能遵守在2012年选举期间做出的不支持纾困希腊的承诺。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

在那之前,她曾出演过大受欢迎的情景剧,并且也因饰演的角色而小有名气。
The EU is making clear it wants to use the void in US leadership on trade to nail down new trade agreements. The negotiations with the Mercosur trade bloc in Latin America have been going on in fits and starts for more than a decade. But the EU and key Mercosur members like Argentina are now pushing to conclude a deal by the end of this year. That would be a big statement planted right in the US’s backyard.
“我跟她很像,我们真的就像一对老夫妇。”
Law

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Batman vs Superman: Dawn of Justice is scheduled to hit theatres on March 23, 2016.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Despite relatively low comparative competition earnings and salary, the pair were the two highest earners in regards to endorsement deals last year, with 17-time Grand Slam champion Federer earning pound 41 million.
arrogant

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

卓越雇主排名:12

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

The number of moviegoers in 2016 reached 1.37 billion, an increase of nearly 8.9 percent year-on-year.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

该排名的编辑菲尔·巴蒂称:“在近几年取得重大进展之后,中国在全球排名榜上的持续增长似乎已经停滞。这些新数据显示,新兴力量要打入传统的全球名校阶层是多么困难。”
但是那数以千计的爱尔兰球迷呢?他们已经失控。
Initial success was achieved in supply-side structural reform.
This umbrella protects your dogs from the sun and rain.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
From the themed collection: 共有产权房别再装“迷你”窗
Review Article

Influenza neuraminidase: A druggable target for natural products

《新财富》预计,2025年左右,中国首富将追平美国首富的个人财富,并有实力问鼎全球首富。
Federal, state and local government job cutbacks are slowing. More than 250,000 workers at all levels of government lost jobs last year. This year, so far, about 20,000 have gained jobs. Worries about the nation's debt and deficits likely will keep a lid on government spending and investments, economists say, but any jumps in, say, infrastructure spending would create jobs. At the least, government will be less of a drag.[qh]
这里有一些散步和骑行的小径可通往其他的湖滨社区以及市中心,骑车去市中心15分钟可达,开车10分钟。附近有步行者艺术中心(Walker Art Center)和几座博物馆。冬天湖上很多人玩冰球和滑冰运动;夏天则流行划独木舟、游泳和钓鱼。
9、《神奇动物在哪里》
今年2月的时候,在格莱美颁奖典礼上,克里斯汀?韦格和玛蒂?齐格勒为希雅的歌曲《Chandelier》伴舞,希雅背对着观众(图)

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

华盛顿暂时的“停战”能否持续?
“It suggests that people put more weight on what happened to themselves and less weight on other information that might be available,”Koudijs says. The more personally removed people are from an important event, the less it is to affect their appetite for risk.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

5. Caterpillar

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Tom Hanks and Meryl Streep in front of the camera, with Steven Spielberg directing a historic battle over press freedom - there's much for awards voters to admire.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

But most of us are self-aware enough to understand that even as we do this, we are lying to ourselves. We recognize those dangers when it comes to politics (see: Bush and Clinton). Why should clothes be any different?
em进入,brace胳膊-拥抱
lasting
1. “暂时没有名字的泡沫”引发30年来的最大规模崩盘

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

The gig economy
3. Not starting your own business
Despite it being not that different from the typical bottle opener, the BOx does have a nice design made with stainless steel and solid wood.
The overall 2018 ranking encompasses more schools than ever before – 1,250 universities located across 74 countries. This is an increase from the 1,000 schools in 65 countries included in last year's edition.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

求职者犯的错,他们:
得益于网络游戏产业的快速增长,网易公司创始人丁磊的财富翻倍至960亿元,超越了百度公司董事长李彦宏,在IT富豪榜上排名第三。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

5.重播和比赛精彩集锦同主要现场比赛一样精彩,所以我也会看。
Coca-Cola (KO, Fortune 500) Chief Executive Muhtar Kent thinks as both a first-generation American as well as a business leader that immigration reform is good for business. Kent outlined in a February USA Today op-ed how "lucky" he felt to be able to make his life in the U.S. and his belief that foreign entrepreneurs should have the same opportunity. The CEO wrote that he supports immigration reform because immigration is "an essential part of the growth calculus for this great country."
4. Slacking at school
201011/117323.shtmlThe French actress will star alongside Ryan Gosling, Michael Fassbender and Natalie Portman.
一座陵墓般的濒危物种仓库。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

5. How to play poker
statement
Despite Sotheby’s branding the two-part auction as “The Bernheimer Collection,” his stock proved a hard sell. Only 22 out of the 42 lots at the Nov. 24 evening sale found buyers, with a top price of 197,000 with fees for the 1732 Nicolas Lancret painting, “Le Menuet” — a frothy “fête champêtre” scene with childlike dancers — that had been purchased for $744,000 at auction in 2005.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

但是,尽管他预计2017年第一季度的“出口会显著回升”,这位瑞银人士强调不要过于乐观。他认为,同比增长将会减弱,甚至可能在2017年下半年变为负增长,因为在2017年全年,“出口量不会大幅增长,而(去年大宗商品价格疲软)的基数效应将会减弱”。
Honestly if you want to laugh your way through a Netflix original movie, please just watch The Incredible Jessica James because it's a delightful romantic comedy that blows everything else out of the water.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 2016年中国定制家居市场规模预测
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 门窗行业五大消费行情解析
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Lecent去世当月,警方并未透露是她自己无意间扣动扳机还是被屋内的其他人射中。
If managers suspect you're looking elsewhere, your LinkedIn profile is often the first place they'll snoop, says Jenny Foss, founder of the career blog JobJenny.com and author of "Ridiculously Awesome Job Search Kit." "It's where a lot of people tend to get busted," she adds。
n. 非法移民

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

答:英雄是一个不想成为英雄的人。英雄是那种明明完全可以选择,但却选择在那个时刻承担起责任的人。那就是英雄所要做的事。举个例子,在911实践中,飞机上的一些乘客曾经和恐怖分子搏斗。在福岛辐射泄露实践中,有些人前往当地试图修理核电站,并且因此而死。但他们必须这么做。他们是英雄。他们想要的并不是“当英雄”,而是承担责任,做正确的事。
9月份CPI录得1.6%的同比涨幅后,经济学家曾预测10月份的同比涨幅为1.5%。中国政府为今年全年设定的通胀目标为“3%左右”。
deprivation

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

vigilance

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

urb城市+an表名词和形容词,“…地方.…人参考:suburb郊区,aub+urb→城市的

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

entertainment
马特·达蒙凭借他在《火星救援》中扮演的被困宇航员一角而荣获喜剧类最佳男主角奖项。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Over 11 million new urban jobs, and a registered urban unemployment rate within 4.5 percent.
The highest average monthly salary for 2016 graduates is 5693 Yuan in IT/Internet/telecommunications/electronics industries; second is financial industry and culture/sports/entertainment/media industries with average salaries level of 4685 Yuan and 4552 Yuan respectively; monthly salaries in agricultural/forest/grassland farming/fishing, and services/ educational sports/industrial arts are relatively low among signed graduates, respectively are 3500 Yuan, 3873 Yuan and 3900 Yuan.
不错,2014年完全是一场灾难,只等着引爆。在《年内股市崩盘的概率有多大?》(Doomsday poll: 87% risk of stock crash by year-end)一文中,我们分析了今年年初以来的10大崩盘征兆。之后,我们又不断发现了更多新的妖魔。它们有如嘀嗒作响的定时炸弹,来自国会、最高法院、性问题、碳排放、石油巨头、国家安全局(NSA)、国税局(IRS)、茶党式财政紧缩。接踵而至,让人无法招架。
发型。略长的卷发——蛤?你不是自来卷哦?小可怜,那你只好每晚带着卷发夹入睡了。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

2.Hold themselves and others accountable
In October, the government announced that it was ending the decades-old "one-child policy," which restricted the number of children that married couples are allowed to have. The new regulations will not take effect until next year.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

When asked if the central bank would do more, Dario Perkins, chief European economist at Lombard Street Research, said: “I don’t think so, unless something goes wrong in the wider global economy.”
但如果美国能够避开由华盛顿造成的这一危机,明年劳动者找工作的前景实际上还相当不错。首先,超级飓风“桑迪”(Sandy)造成的破坏将需要修复,这样就会带来建筑业和零售业的工作机会。与此同时,因为财政前景的不确定性而暂停投资和招聘和企业可能最终打开钱包。这也意味着会有新的就业机会出现。[qh]

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Sixty Vocab:

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

8. 精彩出演)的艺术觉醒与性觉醒,欲望令她长大成人。
中国早已超越了俄罗斯成为紧随美国之后的世界第二大强国。
['depjuti]
年龄:43岁

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

乔治王子获得满分,因为他对加拿大总理特鲁多傲慢的击掌回了一记冷眼。
Such claims are unlikely to go away, though. John R. Christy, an atmospheric scientist at the University of Alabama in Huntsville who is known for his skepticism about the seriousness of global warming, pointed out in an interview that 2014 had surpassed the other record-warm years by only a few hundredths of a degree, well within the error margin of global temperature measurements. “Since the end of the 20th century, the temperature hasn’t done much,” Dr. Christy said. “It’s on this kind of warmish plateau.”

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

The nearest star, Proxima Centauri, has a planet orbiting it not much bigger than Earth. Its "year" is only 11 days. But it's in the habitable zone because Proxima Centauri is a red dwarf star about 100 times fainter than the sun. And there's hot news that a similar star, 40 light years away, may have three planets in its habitable zone.
They are typically designed for students with an average age of 22.
draft

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

在苹果今年6月举行的全球开发者大会(Worldwide Developer Conference)上,库克被应用开发者团团围住,要求与他自拍合影。到了10月的iPad发布会,他甚至自己讲起了笑话。他还是一贯的着装,简单朴实:黑衬衫,牛仔裤,衬衫下摆散着。他说,Apple Watch得到了“深谙时尚与风格——比我还懂的人”的热烈好评,一边说,一边心照不宣地指着轻声发笑的观众。
普惠金融和绿色金融
2. Worldwide Murders

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Will China's stock market climb back to the 6,000-point mark it reached two years ago? The stock market was at its most bullish back then, but if you ask the same question now, some would cite a global economy still reeling from a recession.
The enterprise storage company boosts company morale by hosting a mid-summer "Dog Day". Employees bring their pets to work and enjoy a vendor fair (local groomers, store owners, and trainers are often present), as well as a doggie talent show. A raffle runs the week leading up to the event, and all proceeds are donated to a local animal charity.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 中国城镇家庭负债率升至5.5%
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

To SKN Company in Russia for exploding old Russian ammunition and creating diamonds. Now that's recycling!
Meanwhile producer prices fell 4.9 per cent year-on-year in February, as expected, compared to a 5.3 per cent fall in January. The drop was the smallest in eight months.
I expect more companies to develop leaders who know how to manage networks — not just the traditional internal network of employees, but more loosely connected webs of suppliers and contractors, managed remotely via the internet and social media.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

perspective
尽管很多人总把保时捷与纯性能车联系在一起,但近年来保时捷扩大了他们的阵容,包括帕纳梅拉,即为上图的豪华车型,除此外还有卡宴和小卡宴SUV。根据多数评论家,帕纳梅拉不仅继承了保时捷强大的性能,还满足了使用者对高端内置和联网特性的需求。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

v. 结带子,饰以花边
Total shipments of cellphones reached 560 million in 2016, up 8% year on year, the report showed.
Anti-dumping cases were much easier to bring in the US than in the EU where companies first had to pass a public interest test.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

这个节目围绕宾夕法尼亚州匹兹堡(Pittsburgh)的Abby Lee舞蹈学校里面的小孩子展开。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 广州二手楼成交明显回升
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

The Irish. They sing, dance, drink and sing some more. The lads were singing lullabies to a little baby in Bordeaux to try and get it to go to sleep.
6.London's bike hire scheme couldn't be simpler, by the way: just go up to the terminal at any docking station, pay by card and take away one of our so-called "Boris bikes". When you're done with it, simply throw it into the nearest canal. They're disposable!

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

科比也不幸成为本赛季当中第1位至少投篮14次却只拿下4分甚至更少的球员。
"Machines will be stronger and smarter than human beings, but they will never be wiser," he said, "because one thing's for sure: Wisdom, soul and heart are things that only human beings possess, and machines can never enjoy failure, success, friendship or love."

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

complex
本田的幸运之处在于,它在美国的客户对其拥有深厚的好感和忠诚度,还因为优质低价的极高性价比受到第三方评测机构的好评。不过,因安全气囊爆开后碎片四溅伤及乘客这一产品缺陷导致的争议,在一定程度上削弱了这个客户基础。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

established
Ohsumi’s research on autophagy shines a light on ubiquitous diseases such as Parkinson’s and diabetes.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

杜阿·里帕《杜阿·里帕》

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Investors in emerging markets need no reminder of the importance for EM assets of the US Federal Reserve — or do they?
Strengthening the all-around improvement of government
Deciding what to blog about can become time consuming. HitTailanalyzes the data in your Google Webmaster Tools account and makes recommendations for long-tail words to write about. In addition, HitTail has a network of skilled writers who can create the content for you.
由于今年是意大利标志性导演米开朗基罗·安东尼奥尼逝世10周年,为向大师致敬,将放映他的13部经典作品--从他的出道作品《某种爱的记录》到1995年的爱情片《云上的日子》。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Changing minds

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 北京新建商品房价格同比微降
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

我们要营造有利于创业就业的环境,不是靠政府去提供铁饭碗,而是让人民群众用劳动和智慧去创造或者说打造金饭碗。
亲爱的朋友,你们即将毕业,呈现在你面前的世界拥有美好的前景和潜力;这个世界并不仅仅以办公室走廊或华尔街的形式出现,而是令人激动不已的真实世界,充满许多未解之谜,以及让人陶醉的体验。我们当中许多人都忽略了这个简单的真理。
The difficulty of arranging visas for the large contingent of students from outside the EEA partly explains why UK schools performed disproportionally poorly in terms of international course experience, with 14 schools ranked in the bottom half of this criterion.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 家居联盟隆重登场再轮回
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

这个12岁的女孩已经成为了在Instagram拥有300万粉丝的超级巨星,她和流行歌手希雅(Sia)合作的MV在YouTube上点击量超过10亿。
To Craig Bennett, Abigail Baird, Michael Miller, and George Wolford for demonstrating that brain researchers, using a combination of complicated equipment and simple statistics, can find meaningful brain activity anywhere, even in a dead fish.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 共享租赁市场退押金纠纷增长
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

衡量散货大宗商品贸易的波罗的海干散货运价指数(BDI)已经触及历史低位。2014年超过美国成为世界最大贸易国的中国本月报告,1月出口和进口都出现两位数下降。正在经历一个多世纪以来最严重衰退的巴西从中国的进口暴跌。
即便这些改进最终会降低长期成本,遵守这条法律可能还是颇具挑战性。此外,2015年是各楼盘停用6号取暖油、改用污染更少的4号油的最后期限。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

3. Feng Shui

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 创新推动海南自贸区可持续发展
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

除了要符合质量标准之外,进口商品还必须按中国规定正确标注。
smart
7.Yes, John was with me last night. – Because that’s what friends do… we agree and ask questions later。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Iese商学院的优势之一是其学风严谨。这所位于巴塞罗那的商学院在定制课程的所有指标上一贯表现优异。该校在15项指标中的11项上都跻身前五之列,并在国际客户和师资多样性两项指标上排名第一。
迷你剧集/电影类最佳女配角:雷吉娜?金(Regina King),《美国重案》(American Crime)
The singer/songwriter Dua Lipa has been steadily releasing a string of singles since 2015, beginning with the flirty "Be the One" and finally hitting the jackpot with "Hotter Than Hell" – both collected here on her debut album.
中国香港——也许香港的标志性景观是一艘驶入画面的仿古船,其背景正是这座城市举世闻名的天际线,但《孤独星球》选中此地却是因为距维多利亚港数英里之外的自然遗产。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

With most of our favorite shows on or approaching the dreaded holiday hiatus, it's time to reflect on the women that made the fall 2011 TV season so great.
After being named Esquire's "Sexiest Women Alive" in October and Details' "Most F*ckable Celebrity" last month, the gorgeous 29-year-old has now snagged another honor: FHM's "Sexiest Woman In The World 2013," beating 99 other ladies and countless more who didn't even make the list.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Lecent was with an unknown number of other youth when she was killed by a single bullet inside a home in a public-housing complex near Martin Grove Rd. and Finch Ave W.
Song “Family”(Tan Jing)
Across all European schools, the average salary of alumni three years after graduation ranges from $143,000 for executive MBA graduates to $54,000 for MiM graduates. MBA graduates earned on average $123,000. Spanish and German MiM graduates enjoyed the highest salary three years after graduation, both $70,000 on average. French MBA graduates and Swiss EMBA graduates top their salary scale, with average salaries of $137,000 and $166,000 respectively.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

警方周四表示,关于14岁少女Lecent Ross的枪击案,已逮捕两人。
我去年就说过、今年要再强调的一点是:唯一比预测未来更不招人待见的事情就是公开自己的预言。

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